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Finally, it was demonstrated that the point mutation does not affect the mRNA levels of the VTC1 gene, thus was hypothesized that the point mutation could affect the enzyme activity or stability rather than transcription or mRNA stability ( Structurally, the GMP enzyme from thale cress has a molecular weight of 41 kDa, and apparent molecular weights of ≈80 and 170 kDa (Zhao and Liu, 2016

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Isoalantolactone inhibits the proliferation of human liver cancer cells by inducing intrinsic apoptosis