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Importantly, stem cells have been shown to improve memory and reduce inflammation in Alzheimer’s animal models (4c) (4d), and patients' own MSCs can safely be harvested and prepared for many specific applications with substantial evidence of good safety and effectiveness, with increasing evidence that they can help neural tissue repair, and we continue to investigate their unique benefits in the treatment of ischemic stroke, traumatic neural injury, and neuroregenerative tissue repair (4e) (4f)