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Oral administration of pyroglutamate has been found to benefit age-associated memory impairment (71), alcoholic encephalopathy (72), and delirium induced by anticholinergic medication (73)

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A 2015 review in BioMed Research International, the most-cited summary of GHK’s biology, describes the peptide stimulating both the synthesis and the breakdown of collagen and glycosaminoglycans, while nudging the metalloproteinases and their inhibitors in tandem