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Possible complications heart failure severe neurological deficits gastric cancer type 1 diabetes rheumatoid arthritis myasthenia gravis (a chronic condition causing muscle weakness) Hashimoto’s disease (an autoimmune condition affecting the thyroid) A pregnant or nursing person with a B12 deficiency When a person receives treatment for a B12 deficiency, they generally recover well and cease to have symptoms, although they may need to continue to use B12 nutritional supplements