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It was observed that mitochondria do show notable morphological changes in the capillary endothelial cells in patients with sarcoidosis, as demonstrated in the study carried out by Mochizuki et al., who in 2011 examined tissues of the bronchus and lung obtained from 16 patients and 11 controls and observed a close relationship between mitochondria and lipid droplets in capillary endothelial cells of the respiratory tract

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Knockdown of STAT3 or use of the STAT3 inhibitor W1131 can induce ferroptosis through Fe 2+ accumulation and lipid peroxidation in gastric cancer cells