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DSIP-CBBBP Fusion Peptide — BBB Delivery Research (2024) The 2024 Frontiers in Pharmacology study by Shao and colleagues investigated a DSIP-CBBBP (cell-penetrating peptide) fusion construct expressed in Pichia pastoris in a PCPA-induced insomnia mouse model

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This leads to the dissociation of the G protein subunits, G α and G βγ , from the receptor's cytoplasmic tail (Selvatici et al., 2006