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Cellular Regulation and Gene Expression Studies AHK-Cu has also been investigated in experimental models examining cellular regulation, transcriptional activity, and peptide-mediated signaling pathways

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Extensive HPLC with electrochemical detection and UPLC-MS/MS analyses of the cell media demonstrated that the presence of NAcCys very efficiently shifted the estrogen metabolism towards protective methoxylation and conjugation pathways in multiple ways, while formation of depurinating DNA adducts was inhibited