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However, many aspects remain unsolved with an unmet need to deepen the topic, in relation to the ways in inducing liver damage, and the timing of use/abuse of these drugs, theme that is subject of much controversy, i.e., pain control

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Retinal neovascularization occurs in 36% of eyes with an area of non-perfusion greater than 5 disc diameter.54 RVO is associated with an increase in vascular causes of death (both cerebral and cardiac) in large prospective follow-up studies.55 In all patients with RVO, the systemic risk factors (hypertension, diabetes mellitus, blood lipid disorders) should be investigated and managed by appropriate specialists