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Bus JS, Aust SD, Gibson JE

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Irrespective of whether the bacteria from leaky gut causes infection or not, they release pattern-associated molecular patterns (PAMPs) including LPS that reach the liver and get recognized by toll-like receptors (TLRs) present on hepatic Kupffer cells (KCs), and encourage the production of proinflammatory cytokines and chemokines that chemoattract neutrophils (54)