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OXY could suppress the synthesis of pro-inflammatory mediators in microglia triggered by lipopolysaccharides (LPS) in mouse brain via interaction with mitogen-activated protein kinases (MAPKs) pathway and inhibition of the LPS-stimulated secretion of TNF-α and IL-1β in these microglial cells (Yuan et al., 2016)

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Tamanho:1 quilograma (2,2 libras)

Cario and Podolsky have collected small intestinal and colonic biopsy specimens from IBD patients and observed that TLR4 was strongly upregulated in intestinal epithelium of UC and CD patients [51]