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Prior Heat Stroke Heat-related illnesses, as outlined in TABLE 4, represent a continuum of life-threatening disorders that range in intensity and severity from mild cardiovascular (e.g., heat exhaustion) and CNS abnormalities to profound cellular damage (e.g., heat injury and heat stroke) due to a systemic inflammatory response syndrome (SIRS) in hyperthermic victims (5, 26)

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Findings from both studies are complementary and confirm that the HQLQv2 and FSS are valid and appropriate for use in HDV populations across different liver fibrosis stages, assessing fatigue and HRQoL impacts