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However, the clinical translation of RNA therapies faces significant obstacles, including instability, vulnerability to RNase degradation in the bloodstream and tissues, renal clearance, uptake by the reticuloendothelial system (RES), limited cellular uptake due to size and negative charge, endosomal trapping, off-target effects, and immunogenicity [3]

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we don’t have enough nutrition – vitamins, minerals, antioxidants, amino acids, essential fats - in the body, simply because we aren’t eating enough