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Venous Blood Gas (VBG) analysis identifies acid-base disturbances, such as anion gap metabolic acidosis, which may arise from lactate accumulation due to hepatic necrosis or poor tissue perfusion

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It can activate the Keap1–NRF2/HO-1 axis to suppress lipid peroxidation and ferroptosis (126), and can also enhance mitophagy and dampen excessive inflammation (127), processes that may converge on ferroptosis control