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Of note, the arterio‐venous oxygen saturation difference is lowest in humans and highest in mice

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Vitamin C is also know to act as a pro-oxidant due to the metal catalysed reaction of vitamin C which produces ascorbate free radicals, DHA and H 2 O 2 which are toxic to the lens and if not reduced by a mechanism such as the GSH redox cycle, can result in the formation of highly reactive carbonyls [103]