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Tamaño:100 ml

These studies demonstrated that the antagonists had structural homology with the dimerization domain of the pleiotropic growth factor hepatocyte growth factor (HGF), bound to HGF with high affinity, blocked HGF’s activation and subsequent activation of its receptor c-Met, and displayed both anticancer and antiangiogenic activity as would be expected of an HGF/c-Met antagonist (Peters and Adjei, 2012)