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Moreover, a more recent study examining the gene expression profiles of human fibroid tissues compared to normal myometrial tissue from the Gene Expression Omnibus database determined that proteolipid protein 1 (PLP1), a member of the TNF superfamily, had upregulated mRNA and protein levels in fibroid tissues compared to normal tissues [64]

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Some people report less stiffness, easier recovery, or changes in skin quality, while others notice little difference