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Anelli et al., Cysteines as Redox Molecular Switches Mechanisms ensuring tight redoxstasis control are present in the three cellular compartments where protein folding takes place (cytosol, ER and mitochondria) and they are intimately linked to protein quality control (Anelli et al., A prototypic example is provided by the Nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor whose nuclear translocation is prevented by interactions with Kelch-like ECH-associating protein 1 (Keap1)

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Furthermore, advancements in formulation technologies, such as the application of nanocarriers and sustained-release and controlled-release technologies, may enhance the bioavailability and efficacy of BPC 157, providing more possibilities for its clinical application