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How Temperature Affects Your B12 - Julie Wichlin

Once released, the GR amino acids that interact with the drug are Phe209, Ala319, Ile350 and Val354 at a distance of 2 to 4 Å and also with residues Tyr180, Leu321, Lys318, Leu320, and Thr352 (Thr352 forms several polar and hydrogen bonding interaction at 2.2 to 3.2 Å) that stabilizes the carmustine in the binding pocket (Fig

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As noted above, the transient oxidative stress induced by methionine deprivation may partially result from glutathione depletion