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Research indicates that up to 50% of individuals may require a customized, more frequent injection schedule (such as every 2 to 4 weeks) to remain completely free of symptoms [2]

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mPEG–PLGA NPs (ratio 1:4) release NO that can promote angiogenesis, whereas mPEG–PLGA NPs (ratio 1:1) generate a relatively high concentration of NO, which can induce an antibacterial response or apoptosis