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These findings, together with various oligomerization states of VP35 in different filoviruses 16 , imply that the differences in VP35 dynamics among the filoviruses may dictate the potential divergent mechanisms of replication and pathogenesis during viral propagation

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Overall, these findings highlight the importance of redox homeostasis and metabolic compensation in pathogen adaptation to the host environment and suggest new avenues for antifungal drug development

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