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Additionally, oxidative stress products like reactive oxygen species (ROS) and reactive nitrogen species (RNS) can also activate the NF-κB signal through Toll-like receptors 2 and 4, producing cytokines and chemokines and initiating an inflammatory response.In summary, both oxidative stress and immune imbalance play crucial roles in the pathogenesis of vitiligo, potentially with distinct dominant stages

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Synthesis and biological evaluation of novel flavonols as potential anti-prostate cancer agents