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For example, pseudouridine analogs include but are not limited to 1-carboxymethyl-pseudouridine, 1-propynyl-pseudouridine, 1- taurinomethyl-pseudouridine, 1 -taurinomethyl-4-thio-pseudouridine, 1 - methylpseudouridine l-methyl-4-thio-pseudouridine 3 ψ), 2-thio-l -methyl-pseudouridine, 1-methyl- 1-deaza-pseudouridine, 2-thio-l -methyl- 1-deaza-pseudouridine, dihydropseudouridine, 2- thio-dihydropseudouridine, 2-methoxyuridine, 2-methoxy-4-thio-uridine, 4-methoxy- pseudouridine, 4-methoxy-2-thio-pseudouridine, Nl -methyl-pseudouridine, l-methyl-3- (3-amino-3-carboxypropyl)pseudouridine (acp 3 ψ), and 2'-0-methyl-pseudouridine (\|/m)