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In epithelial cells, inhibiting ABHD17 increases plasm membrane localization of NOD2, leading to NF-κB activation and pro-inflammatory cytokines production, consequently promoting Crohn’s disease [148]

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DNase-I treatment showed more single colonies uniformly distributed on the surface, whereas CLSM images revealed amylase and Proteinase treatment showed a mixture of small and big clusters in biofilm architecture (Figure 3C)